Late final month, the San Francisco-based startup HeHealth introduced the launch of Calmara.ai, a cheerful, emoji-laden web site the corporate describes as “your tech savvy BFF for STI checks.”
The idea is straightforward. A consumer involved about their companion’s sexual well being standing simply snaps a photograph (with consent, the service notes) of the companion’s penis (the one a part of the human physique the software program is educated to acknowledge) and uploads it to Calmara.
In seconds, the location scans the picture and returns one in every of two messages: “Clear! No seen indicators of STIs noticed for now” or “Maintain!!! We noticed one thing sus.”
Calmara describes the free service as “the subsequent smartest thing to a lab check for a fast test,” powered by synthetic intelligence with “as much as 94.4% accuracy price” (although finer print on the location clarifies its precise efficiency is “65% to 96% throughout numerous situations.”)
Since its debut, privateness and public well being consultants have pointed with alarm to a lot of vital oversights in Calmara’s design, comparable to its flimsy consent verification, its potential to obtain little one pornography and an over-reliance on photos to display screen for situations which might be usually invisible.
However at the same time as a rudimentary screening software for visible indicators of sexually transmitted infections in a single particular human organ, checks of Calmara confirmed the service to be inaccurate, unreliable and susceptible to the identical type of stigmatizing data its mother or father firm says it desires to fight.
A Los Angeles Occasions reporter uploaded to Calmara a broad vary of penis photos taken from the Facilities for Illness Management and Prevention’s Public Well being Picture Library, the STD Heart NY and the Royal Australian School of Common Practitioners.
Calmara issued a “Maintain!!!” to a number of photos of penile lesions and bumps attributable to sexually transmitted situations, together with syphilis, chlamydia, herpes and human papillomavirus, the virus that causes genital warts.

Screenshots, with genitals obscured by illustrations, present that Calmara gave a “Clear!” to a photograph from the CDC of a extreme case of syphilis, left, uploaded by The Occasions; the app stated “Maintain!!!” on a photograph, from the Royal Australian School of Common Practitioners, of a penis with no STIs.
(Screenshots through Calmara.ai; photograph illustration by Los Angeles Occasions)
However the website failed to acknowledge some textbook photos of sexually transmitted infections, together with a chancroid ulcer and a case of syphilis so pronounced the foreskin was now not in a position to retract.
Calmara’s AI regularly inaccurately recognized naturally occurring, non-pathological penile bumps as indicators of an infection, flagging a number of photos of disease-free organs as “one thing sus.”
It additionally struggled to tell apart between inanimate objects and human genitals, issuing a cheery “Clear!” to pictures of each a novelty penis-shaped vase and a penis-shaped cake.
“There are such a lot of issues mistaken with this app that I don’t even know the place to start,” stated Dr. Ina Park, a UC San Francisco professor who serves as a medical advisor for the CDC’s Division of STD Prevention. “With any checks you’re doing for STIs, there may be all the time the potential of false negatives and false positives. The problem with this app is that it seems to be rife with each.”
Dr. Jeffrey Klausner, an infectious-disease specialist at USC’s Keck College of Medication and a scientific adviser to HeHealth, acknowledged that Calmara “can’t be promoted as a screening check.”
“To get screened for STIs, you’ve obtained to get a blood check. You need to get a urine check,” he stated. “Having somebody have a look at a penis, or having a digital assistant have a look at a penis, is just not going to have the ability to detect HIV, syphilis, chlamydia, gonorrhea. Even most circumstances of herpes are asymptomatic.”
Calmara, he stated, is “a really completely different factor” from HeHealth’s signature product, a paid service that scans photos a consumer submits of his personal penis and flags something that deserves follow-up with a healthcare supplier.
Klausner didn’t reply to requests for extra remark in regards to the app’s accuracy.
Each HeHealth and Calmara use the identical underlying AI, although the 2 websites “could have variations at figuring out problems with concern,” co-founder and CEO Dr. Yudara Kularathne stated.
“Powered by patented HeHealth wizardry (suppose an AI so sharp you’d suppose it aced its SATs), our AI’s been battle-tested by over 40,000 customers,” Calmara’s web site reads, earlier than noting that its accuracy ranges from 65% to 96%.
“It’s nice that they disclose that, however 65% is horrible,” stated Dr. Sean Younger, a UCI professor of emergency medication and government director of the College of California Institute for Prediction Expertise. “From a public well being perspective, in case you’re giving folks 65% accuracy, why even inform anybody something? That’s doubtlessly extra dangerous than useful.”
Kularathne stated the accuracy vary “highlights the complexity of detecting STIs and different seen situations on the penis, every with its distinctive traits and challenges.” He added: “It’s necessary to grasp that that is simply the start line for Calmara. As we refine our AI with extra insights, we count on these figures to enhance.”
On HeHealth’s web site, Kularathne says he was impressed to begin the corporate after a good friend turned suicidal after “an STI scare magnified by on-line misinformation.”
“Quite a few physiological situations are sometimes mistaken for STIs, and our know-how can present peace of thoughts in these conditions,” Kularathne posted Tuesday on LinkedIn. “Our know-how goals to deliver readability to younger folks, particularly Gen Z.”
Calmara’s AI additionally mistook some physiological situations for STIs.
The Occasions uploaded a lot of photos onto the location that have been posted on a medical web site as examples of non-communicable, non-pathological anatomical variations within the human penis which might be generally confused with STIs, together with pores and skin tags, seen sebaceous glands and enlarged capillaries.
Calmara recognized each as “one thing sus.”
Such inaccurate data may have precisely the other impact on younger customers than the “readability” its founders intend, stated Dr. Joni Roberts, an assistant professor at Cal Poly San Luis Obispo who runs the campus’s Sexual and Reproductive Well being Lab.
“If I’m 18 years outdated, I take an image of one thing that could be a regular prevalence as a part of the human physique, [and] I get this that claims that it’s ‘sus’? Now I’m stressing out,” Roberts stated.
“We already know that psychological well being [issues are] extraordinarily excessive on this inhabitants. Social media has run havoc on folks’s self picture, price, despair, et cetera,” she stated. “Saying one thing is ‘sus’ with out offering any data is problematic.”
Kularathne defended the location’s alternative of language. “The phrase ‘one thing sus’ is intentionally chosen to point ambiguity and counsel the necessity for additional investigation,” he wrote in an electronic mail. “It’s a immediate for customers to hunt skilled recommendation, fostering a tradition of warning and accountability.”
Nonetheless, “the misidentification of wholesome anatomy as ‘one thing sus’ if that occurs, is certainly not the result we purpose for,” he wrote.
Customers whose pictures are issued a “Maintain” discover are directed to HeHealth the place, for a charge, they will submit further pictures of their penis for additional scanning.
Those that get a “Clear” are instructed “No seen indicators of STIs noticed for now . . . However this isn’t an all-clear for STIs,” noting, appropriately, that many sexually transmitted situations are asymptomatic and invisible. Customers who click on by way of Calmara’s FAQs may even discover a disclaimer {that a} “Clear!” notification “doesn’t imply you possibly can skimp on additional checks.”
Younger raised considerations that some folks would possibly use the app to make fast selections about their sexual well being.
“There’s extra moral obligations to have the ability to be clear and clear about your information and practices, and to not use the everyday startup approaches that loads of different firms will use in non-health areas,” he stated.
In its present kind, he stated, Calmara “has the potential to additional stigmatize not solely STIs, however to additional stigmatize digital well being by giving inaccurate diagnoses and having folks make claims that each digital well being software or app is only a massive sham.”
HeHealth.ai has raised about $1.1 million since its founding in 2019, co-founder Mei-Ling Lu stated. The corporate is presently searching for one other $1.5 million from buyers, in response to PitchBook.
Medical consultants interviewed for this text stated that know-how can and needs to be used to cut back boundaries to sexual healthcare. Suppliers together with Deliberate Parenthood and the Mayo Clinic are utilizing AI instruments to share vetted data with their sufferers, stated Mara Decker, a UC San Francisco epidemiologist who research sexual well being schooling and digital know-how.
However in the case of Calmara’s strategy, “I mainly can see solely negatives and no advantages,” Decker stated. “They may simply as simply change their app with an indication that claims, ‘If in case you have a rash or noticeable sore, go get examined.’”