Meanwhile, for Folie À Deux’s London premiere on Wednesday, her approach was a lot more literal.
Gaga was pictured making her way into the event in a floor-length red dress with some enormous shoulder details.
However, it was her hair and makeup that really caught our attention, with Gaga sporting a red bob hairstyle for the occasion, along with bright blue eyeshadow and single tear detail.
The Grammy winner walked the red carpet with her Joker co-star Joaquin Phoenix, who kept things decidedly more simple in a black suit and trainers.
The clip sees Gaga exploring the Louvre museum in Paris at night-time, before giving the Mona Lisa a Joker-esque makeover.
Gaga puts her own spin on the iconic Batman villain Harley Quinn in Folie À Deux, alongside Joaquin, who reprises his role from the first Joker film.
Unlike its predecessor, though, Folie À Deux incorporates musical elements, with both Joaquin and Gaga performing covers of standards made popular by Judy Garland, Frank Sinatra and The Carpenters in the sequel.
Joker: Folie À Deux hits cinemas on Friday 4 October.