Mechanical issues plagued the midfield with Alpine’s Pierre Gasly retiring due to an engine failure and Williams’ Alex Albon also failing to finish, with commentators suggesting debris many have been caught in his car.
McLaren’s Oscar Piastri started eighth on the grid but copped a five-second penalty after a false start.
The Melburnian finished in seventh place, wounding McLaren’s standings in the constructor’s championship.
Qualifying was delayed earlier in the weekend after Williams rookie Franco Colapinto clipped the wall and slammed into the barrier, littering the track with shattered debris.
The Argentinian suffered an impact of 50G but was cleared to race after passing a medical evaluation, starting the grand prix from pit lane.
The glitz and glam of the Las Vegas Grand Prix attracted numerous Hollywood A-listers including model Winnie Harlow, actor Sylvester Stallone, singer Adele and chef Gordon Ramsay.
Actor Brad Pitt was also spotted on track earlier in the weekend, filming scenes for his upcoming motorsport film F1 – for which Mercedes driver Lewis Hamilton is serving as the executive producer.
Footage showed the actor stumbling away from a crash, clouded by smoke before collapsing on the ground.
While the drivers’ championship is over, the battle for the constructors’ championship is still wide open.
Red Bull are still third in the fight for the constructors’ title, on 555 points – trailing McLaren (608) and Ferrari (584).
There are only two rounds of the season left – Qatar from November 29 to December 1, and the season finale in Abu Dhabi from December 6 to 8.