TRAMP assembly alters the conformation and RNA binding of Mtr4 and Trf4-Air2

Proceedings of the National Academy of Sciences, Volume 122, Issue 1, January 2025. <br/>SignificanceSurveillance pathways mediated by the TRAMP complex and the nuclear exosome are critical for maintaining cellular RNA fidelity and homeostasis. Defects in these pathways relate to various diseases. Precisely how TRAMP assembles and recognizes …



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