Transferrin promotes fatty acid oxidation and liver tumor growth through PHD2-mediated PPARα hydroxylation in an iron-dependent manner

Proceedings of the National Academy of Sciences, Volume 122, Issue 5, February 2025. <br/>SignificanceCompared to normal cells, tumor cells exhibit distinctive traits in iron and lipid metabolism, granting them a selective advantage in enduring and propagating amid challenging microenvironmental circumstances, including nutrient stress. …



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