Enzo Maresca’s side started off their campaign with a 4-2 win against Gent at Stamford Bridge last time out, a game which saw the Blues’ boss heavily rotate and give minutes to some of his fringe players, with Christoper Nkunku notably scoring a hat-trick.
Chelsea are massive favourites to win the competition given their resources, and form so far this season, but will likely face one of their tougher games away to the Greek giants despite their mixed start to the domestic season.
Here’s everything else you need to know…
Date, kick-off time and venue
Panathinaikos vs Chelsea is scheduled for a 5:45pm BST kick off on Thursday, October 24, 2004.
The match will take place at the Athens Olympic Stadium.
Where to watch Panathinaikos vs Chelsea
TV channel: In the UK, the game will be televised live on TNT Sports 1, with coverage starting at 5pm.
Live stream: Subscribers will be able to watch on a live stream via the Discovery + app.
Free highlights: The TNT YouTube channel will show highlights from 8pm.
Live blog: You can follow all the action on matchday via Standard Sport’s live blog.
Panathinaikos vs Chelsea team news
As mentioned, Maresca is likely to shuffle his deck, with widespread changes expected from the team that started at Anfield on Sunday. Reece James is fit again but has been rested for this game, along with Nicolas Jackson and Levi Colwill.
Reece James is back in action for Chelsea
Chelsea FC via Getty Images
Panathinaikos vs Chelsea prediction
Even with a so-called “second-string” side set to play again, Chelsea are a cut above every other side in the competition, and should make it two wins from two in Athens.
Head to head (h2h) history and results
This is the first meeting between the two clubs.
Panathinaikos vs Chelsea odds
Panathinaikos to win: 9/2
Chelsea to win: 4/7
Odds via Betfair (subject to change).
